Medication Reconciliation Guide

Medication Reconciliation Process

  1. Verify patient allergies
  2. Develop a list of patient’s medical conditions
  3. Obtain a medication history from the patient, family member(s), and/or caregiver including
    1. A list of all prescription and non-prescription drugs (OTCs), vitamins, supplements, herbals, and alternative medicines
    2. Dose, frequency, formulation, and route of administration for each item on the list
    3. How the patient is actually taking and administering each medication
  4. Compare this list with at least one of the following:
    1. Pharmacy dispensing records
    2. Labels on the patient’s medication bottles
    3. Records obtained from other providers (e.g. physicians, other pharmacies the patient uses, hospital [for recently discharged patients])
  5. Obtain patient vaccination history
  6. Review completed medication list for the following:
    1. Discrepancies between medication history sources
    2. Medication adherence issues
    3. Medication-related problems (see table 1)
  7. Create and document a plan for addressing items identified during the medication reconciliation

Table 1. Medication-related problems

Incorrect or missing medicationMedication omission
Medication addition
Duplicate therapy
Medication without indication
Indication without medication
Potential for adverse effectHistory of allergy or intolerance
Dose too high
Unclear/incorrect instructions
Drug-drug or drug-disease state interaction
Lack of appropriate monitoring
Potential impact on therapeutic efficacyDose too low
Inappropriate frequency
Inappropriate therapy duration
Unclear/incorrect route of administration
Incorrect dose timing
Drug-drug or drug-disease state interaction
Drug-food interactions
Incomplete drug regimen
Incorrect medication administration
Inappropriate medication storage
The PCNE Classification V 9.1

References

  1. International Pharmaceutical Federation (FIP). Medicines reconciliation: A toolkit for pharmacists. The Hague: International Pharmaceutical Federation; 2021
  2. Pharmaceutical Care Network Europe Association. The PCNE Classification V 9.1. https://www.pcne.org/upload/files/417_PCNE_classification_V9-1_final.pdf
  3. Barnsteiner JH. Medication Reconciliation. In: Hughes RG, editor. Patient Safety and Quality: An Evidence-Based Handbook for Nurses. Rockville (MD): Agency for Healthcare Research and Quality (US); 2008 Apr. Chapter 38. Available from: https://www.ncbi.nlm.nih.gov/books/NBK2648/
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